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Starting with lower doses (available through the Microdose protocol) reduces initial side effects while maintaining medication costs

The treatment is approved for adolescents aged 12 and older who have a BMI that falls at or above the 95th percentile for their age and sex

18 The prescribing information for oral semaglutide notes that the most common side effects with use include nausea, abdominal pain, diarrhea, decreased appetite, vomiting, and constipation

It works by stimulating the pancreas to produce insulin in response to food, slowing digestion to promote satiety, suppressing appetite signals, and stimulating the growth of pancreatic beta cells that regulate blood sugar