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Molecular pharmacology of topiramate: Managing seizures and preventing migraine

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Therefore, to eliminate the potential baseline effect of different studies, the rates of body weight change from the initial values were selected as the therapeutic index, which was a better indicator used to assess changes in body weight

This is due to central anticholinergic effects such as confusion, agitation, hallucinations, and somnolence may occur

It is typically taken by mouth one time per day for about three to 16 weeks