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Notoginsenoside R1 promoted HO-1 expressions to reduce oxidative stress-induced apoptosis and kidney fibrosis in HK-2 cells and C57BL/6J mice [146]

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The recipes in this guide prioritize fiber alongside protein for exactly this reason

Adding a GLP-1 medication to their regimen, under provider supervision, may be the more effective path forward

For example, a three-month course of lactulose therapy significantly improved sleep quality, reduced daytime sleepiness, and increased sleep duration and REM sleep in patients with minimal HE (39)