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In autonomic regulation, DCA initially reduces heart rate via reflex mechanisms but subsequently activates sympathetic pathways to maintain HR

According to the Summary of Product Characteristics (SmPC) for these medications, headache is classified as very common (affecting more than 1 in 10 people) with weight-management doses of GLP-1 receptor agonists such as Wegovy (semaglutide 2.4 mg) and Saxenda (liraglutide 3 mg)

Using it off-label for weight loss would require much higher doses than it is currently approved for and it would not be cost effective

GLP-1 receptor agonists in diabetes for stroke prevention: a systematic review and meta-analysis

Do not adjust your diabetes medicines without first seeking advice from your prescribing clinician