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When comparisons were made with other oral drugs used in type 2 diabetes, the reductions in HbA 1c were comparable with glitazones, but slightly less than with metformin or sulphonylureas

Type 2 diabetes can be challenging enough to manage without the added risk of chronic kidney disease, and I have seen in my own practice that patients with type 2 diabetes and chronic kidney disease need extra support from medications that may have a profound clinical impact by lowering the risk of major kidney and cardiovascular outcomes, said Richard E Pratley (AdventHealth Diabetes Institute, Orlando, USA) co-chair of the FLOW trial

Here, the focus is specifically on how their dosing systems compare