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These cells contribute to the permeability and integrity of the BBB through their intimate anatomical relationship (Liebner et al., Every constituent cell of the NVU contributes to the BBBs integrity, and any dysfunction might result in the barrier breakdown, with dramatic consequences such as neuroinflammation and neurodegeneration (Kempuraj et al., 2019)

Researchers studying cell-matrix interactions, enzymatic tissue remodeling, and genomic responses utilize GHK-Cu for the remodeling of the extracellular matrix and modulates anti-inflammatory cytokines along with KPV and Glutathione

[DOI] [PubMed] Yu YC, Mao YM, Chen CW, Chen JJ, Chen J, Cong WM, et al

Furthermore, cysteamine has been recognized as an efficient depigmenting agent for melasma treatment (Besouw et al., 2013)

This risk does not apply to oral or injection forms at standard doses