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Using the qPCR technique, Starkey Lewis and coworkers (Starkey Lewis et al

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35,36 Cells in biofilms enter a slow-growing state and are up to 1,000 times more resistant to antibiotics

Researchers found that, compared with healthy controls, the levels of trimethylamine oxide, glutamine, and lactic acid in the plasma of patients with depression were significantly increased, while the levels of phenylalanine, valine, alanine, glycine, leucine, citrate, choline, lipids, and glucose were significantly decreased