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In human clinical research programs, dosing commonly begins at 2.5 mg once weekly and increases in 2.5 mg increments every four weeks
PAS-stained sections were evaluated using a complementary scoring system assessing tubular brush border loss (02), protein cast formation (03), glomerular basement membrane thickening (02), and tubular dilatation (03)
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Therefore, subsequent aspects of the analyses looked at subsets of the data with longer therapy durations which may have reflected a more genuine post therapy cessation weight delta
