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This paper builds into decades of work from us and others into the understanding of genetics of obesity and predictors of response to obesity intervention, Acosta said

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Comprehensive and in-depth dissection of the regulatory mechanisms, signaling networks and pathophysiological significance of ferroptosis can not only more clearly reveal its intrinsic association with DR, but also hold great promise for identifying novel diagnostic and therapeutic targets for DR, further deepen the understanding of the intricate pathophysiological processes of DR, and lay a fundamental theoretical foundation for developing precise and efficient ferroptosis-targeted therapeutic regimens for DR

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