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The human gene encodes for two isoforms of the enzyme, namely PEMT1, which is localized in the endoplasmic reticulum and generating most of the PEMT activity, and PEMT2, a liver specific isoform exclusively localized in mitochondriaassociated membranes (Tessitore et al., 2003)
Since Figure 3 does not provide a clear quantitative comparison of the oxygen consumption kinetics of the IDYs and the other antioxidants, we applied the kinetic model proposed by Pascual et al
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