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Soybean isoflavones ameliorate ischemic cardiomyopathy by activating Nrf2-mediated antioxidant responses

For immunoregulation, butyrate activates GPR41/43/109A receptors to promote Treg differentiation and, as a histone deacetylase inhibitor, remodels chromatin structure, upregulates anti-fibrotic gene expression, and directly inhibits TGF- signaling to reduce COL1A1 expression at both mRNA and protein levels (Wang et al., 2022)

Verma N, Manna SK (2015) Advanced glycation end products (AGE) potently induce autophagy through activation of RAF protein kinase and nuclear factor B (NF-B)

These oral supplements can complement the effects of glutathione iv treatment and help maintain the results

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