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doi: 10.1016/j.febslet.2008.04.038 230 MottilloEPDesjardinsEMFritzenAMZouVZCraneJDYabutJMet al
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Ferroptosis is readily harnessed in cell culture, where it is induced by GSH depletion (e.g., by erastin) [58] or GPX4 inhibition (e.g., by RSL3) [49] and selectively rescued by potent radical trapping agents (e.g., ferrostatin and liproxstatin, which are not developed for human use) [59, 60]
Moreover, GSTs are involved in c-Jun N-terminal kinase (JNK) signaling pathway
Glutathione helps protect brain cells from damage, which may improve memory and concentration
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