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Furthermore, the authors validated the capacity of MnO 2 -coated mesoporous silica nanoparticles (MSNs) to control drug release, and the camptothecin (CPT)-loaded MnO 2 -MSNs showed sustained CPT release after the addition of GSH (Figure 1G)

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Using RT, we were able to monitor the dynamic changes of GSH in living cells, which subsequently led to the observation of enhanced antioxidant capability of activated neurons and time-dependent changes of GSH during the ferroptosis process