superoxide radical, hydrogen peroxide, hydroxyl radicals, peroxyl radicals, nitric oxide, peroxynitrite), and their role in oxidative damage of DNA, proteins, and membrane lipids
Membrane pore formation via GSDMD oligomerization was induced in meningioma cells after 8803 treatment, thereby allowing release of damage-associated molecular patterns (DAMPs) that synergistically activate local immune populations and result in upregulation of collagen-degrading genes
All-in-one theranostic nanoagent with enhanced reactive oxygen species generation and modulating tumor microenvironment ability for evffective tumor eradication
Discussion Compared to individual parameters, composite biomarkers may provide a more robust method for evaluating disease progression in response to a study intervention than a single efficacy outcome [28]