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Prevention and Management of Chemotherapy-Induced Peripheral Neuropathy in Survivors of Adult Cancers: ASCO Guideline Update

In addition, GLP-1R stimulation activates insulin signaling pathways and regulates gene expression, decreasing systemic insulin resistance and brain insulin resistance in patients with AD (Dahiya et al., 2025)

Large peptide molecules are fragile

These medications all belong to the GLP-1 receptor agonist class and work similarly in the body

The key functions of these interactions can be divided into three main aspects: mitochondrial quality control, clearance of metabolic waste and nutrient recycling, and integration of ROS signaling with cellular metabolism