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This causes harmful buildup, slows cell growth, triggers inflammation, and leads to chronic diseases

Redefining the relevance of established cancer cell lines to the study of mechanisms of clinical anti-cancer drug resistance

Solvent effects were included using a polarizable continuum model (PCM)

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Such a non-protein cofactor is known as a "prosthetic group." R -lipoic acid functions as a prosthetic group for the biological activity of the following multienzyme complexes: The glycine cleavage system that catalyzes the decarboxylation of glycine coupled with the addition of a methylene group (-CH 2 ) to tetrahydrofolate to form 5,10-methylene tetrahydrofolate, an important cofactor in the synthesis of nucleic acids ( Figure 3 )