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The practical implication is simple but important

Kleiverda G (1996)

Supplementing melatonin in aged rodents has been shown to improve mitochondrial respiration efficiency, reduce lipid peroxidation, and even extend lifespan in some studies

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In cardiovascular and cerebrovascular research , this compound's capacity to reduce oxidative stress, inhibit vascular smooth muscle cell migration, and protect against ischemia-reperfusion injury supports its potential application in preventing and treating atherosclerosis, restenosis, and stroke [2]