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PubMed laboratory research record [PMID: 22655244] PubMed record related to this compound for laboratory literature review

For example, microbial GABA produced in the colon may interact with enteric or vagal GABA receptors, potentially influencing anxiety-like behavior in mice [51]

Based on the evidence that heat-shock proteins (Hsps) can exert neuroprotective effects against oxidative stress-related injury and that nutritional antioxidants are able to upregulate Hsps in neurons, use of nutritional antioxidants such as carnitine/acetyl-L-carnitine has been advocated to counteract the oxidative stress-induced brain damage in Alzheimer's disease [67, 119]

Despite its methodological limitations, this study provides a foundation for future controlled studies aimed at refining topical antioxidant-based therapies and advancing personalized approaches for this multifactorial pain disorder