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Similar to the inflammatory sequence observed in radiation-induced lung injury, the immune response triggered by REE particles may sequentially undergo a neutrophil peak phasemacrophage-dominant phaselymphocyte-regulatory phase, ultimately determining whether acute injury is repaired or progresses to chronic pathology (116) (see Figure 4a)

Those with known sensitivities to sulfur-containing compounds should exercise particular caution

Meta-analysis was performed using a random-effects model

Oijen AH et al