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These findings align with earlier investigations in high glucoseinduced C57BL/6 mice treated with PB2, indicating that PCs regulate lipid metabolism in diabetes by targeting endoplasmic reticulum sensors such as PERK, IRE1, and ATF6 (Liu Z
Su-yuan, C., Xiao-jing, L., & Jian-hui, L
[11] [12] For weight management, NICE (TA875, TA664) recommends these medications for adults with a BMI of 35 kg/m or more (or 32.5 kg/m or more for people from South Asian, Chinese, other Asian, Middle Eastern, Black African or African-Caribbean family backgrounds) who have at least one weight-related comorbidity and are receiving care through specialist weight management services
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