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Evidence supporting combined therapy is emerging but remains limited as a recent meta-analysis of randomized controlled trials reported lower risk of HF hospitalization with concomitant SGLT2 inhibitor and GLP-1 receptor agonist therapy compared with monotherapy or standard care [24]

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In sex-specific analysis of CVD events, we used individual-level data from UK Biobank

Healthcare professionals should maintain awareness of the warnings and precautions and ensure these are reassessed if new family history information emerges