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Interestingly, in echidna GLP-1 there is less conservation of the receptor binding residues with additional changes at the N-terminal receptor binding Phe 12 (conservatively substituted to Tyr) and Asp 15 (changed to Glu) residues
10.47363/JJCMR/2023(3)145 66 HamaguchiT.OnoK.MuraseA.YamadaM
Poor Hydration Dehydration can worsen constipation and fatigue
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