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This work suggests that we may have overlooked a third phase, perhaps the most challenging one: maintaining the result over the long term

Takeaway Glucagon-like peptide-1, commonly referred to as GLP-1, is a natural hormone made by the body to stimulate insulin secretion after a meal

Headaches were not reported frequently enough in Ozempic clinical trials to be listed among the drugs common side effects, though they have been reported as a side effect after the drug came to market

Further randomised controlled and pragmatic trials are needed to define their potential benefits/harms, mechanisms of action and where GLP1RAs might fit into existing treatment pathways for uncontrolled asthma

These products aim to provide more effective saliva replacement, longer-lasting oral moisture, and enhanced antimicrobial protection tailored to the specific bacterial shifts that occur during GLP-1 treatment