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10.1016/j.cell.2014.02.055 C

Synthesis of glutathione (GSH) and superoxide dismutase (SOD) is elevated, supporting free radical neutralization and cellular maintenance

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[26] The same critics claimed that previous controlled trials "found no evidence that chelation is superior to placebo for treatment of CAD [Coronary Artery Disease] or PVD [Peripheral Vascular Disease]," making the trial "unethical, dangerous, pointless, and wasteful." [3] Evidence of insurance fraud and other felony convictions among (chelation proponent) investigators further undermined the credibility of the trial

Pushing past these limits does not accelerate results and may cause metabolic adaptation