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Additionally, intravascular hemolysis results in renal injury, which develops as a consequence of filtering hemoproteins released from hemolytic red cells by the kidneys [229]

The study found that H 2 S pretreatment of ECs can improve mitochondrial function and cell viability after hypoxia treatment by activating extracellular regulated protein kinases (ERK) 1/2, as well as enhance ECs migration and angiogenesis, thereby protecting ECs from ischemia/reperfusion injury and gradually reducing cardiac damage (97)

29 FahadS.NieL.ChenY.WuC.XiongD.SaudS.et al (2015b)

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