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Retatrutides heart-rate increase has averaged around 6.7 bpm at 12 mg, peaking around week 24 and declining thereafter

[PMID: 8992990] PubMed record related to this compound for laboratory literature review

Take 1 - 2 capsules daily, preferably with a meal or as recommended by your healthcare professional

Additionally, both tirzepatide and berberine can cause gastrointestinal side effects including nausea, diarrhea, and abdominal discomfort, which may be additive when used together