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SGLT-2i trials (EMPA-REG OUTCOME [Cardiovascular Outcomes, and Mortality in Type 2 Diabetes], 32 CANVAS [Canagliflozin and Cardiovascular and Renal Events in Type 2 Diabetes], 33 and DECLARE-TIMI 58 [Dapagliflozin Effect on Cardiovascular Events] 34 ) also had similar patient population (mean age ranged from 63 to 64 years

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