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Frontiers in Pharmacology , 13
Tissue-Level Interpretation Changes in body weight or adipose mass can result from altered food intake, hydration, lean mass, lipid synthesis, lipid mobilization, substrate oxidation, activity, thermogenesis, gastrointestinal effects, or tissue-specific adaptation
Serious risks and contraindications Serious but less common risks include: NCBI+2NCBI+2 Pancreatitis (inflammation of the pancreas) Gallbladder disease , such as gallstones or cholecystitis Acute kidney injury , often linked to severe dehydration from vomiting or diarrhea Potential worsening of diabetic retinopathy in some people with rapidly improved blood sugar Semaglutide products carry a boxed warning for thyroid C-cell tumors, based on rodent studies
New Orleans, p 575 Chernausek SD, Backeljauw PF, Frane J, Kuntze J, Underwood LE
It reduces glucagon (a hormone that raises blood sugar), which can improve blood-sugar control
