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H., Petrovic, A., & Seiwerth, S
In alignment with other GLP-1RAs, severe or blood glucose-confirmed symptomatic hypoglycemia was infrequent in the PIONEER programs, although it seemed to occur more frequently in trials combining oral semaglutide with sulfonylureas (SU) or insulin (PIONEER 3, 5, 7, and 8) [8, 10, 12, 13]
The absolute risk difference is small, but the relative doubling is consistent across multiple trials
Instruct patients to inform healthcare providers prior to any planned surgeries or procedures if they are taking RYBELSUS
& Forman, H
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