Excess amounts excrete through urine without causing harm
Patients taking medications with a narrow therapeutic index, including some antiseizure medications, should be monitored closely, as delayed gastric emptying from GLP-1 receptor agonists may affect drug absorption
This dual action has been shown in clinical trials to produce significant reductions in HbA1c (a marker of long-term blood glucose control) and body weight, often outperforming medications that target only one hormone pathway
doi: 10.1046/j.1471-4159.1997.69020791.x 139 Mendez-DavidI.HenR.GardierA
Courreges JP, Vilsboll T, Zdravkovic M, Le-Thi T, Krarup T, Schmitz O, Verhoeven R, Buganova I, Madsbad S: Beneficial effects of once-daily liraglutide, a human glucagon-like peptide-1 analogue, on cardiovascular risk biomarkers in patients with Type 2 diabetes