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Reduced appetite (your brain thinks youve eaten enough)
Contact your clinician right away if you see a larger area of bruising, increasing pain at the injection site, a spreading rash, skin changes that do not get better within a few days, or signs of infection, such as: Warmth Pus Fever When to Get Emergency Care Go to the emergency room now if you develop signs of an allergic reaction, such as: Hives Swelling of the face or tongue Trouble breathing
[31] [32] Patients with type 2 diabetes taking tirzepatide often have multiple overlapping risk factors, including advanced age, metformin use, and potential dietary restrictions, making them a particularly vulnerable population requiring vigilant monitoring
Real-world safety data from the FDA Adverse Event Reporting System suggests that Mounjaro may actually have lower pancreatitis risk compared to some other GLP-1 receptor agonists: Mounjaro (tirzepatide): Adjusted ROR 2.74 (suggests the reporting rate is about 2.7 times higher than would be expected if there was no association) Liraglutide (Saxenda): ROR 4.76 (suggests the reporting rate is about 4.8 times higher than expected, making it higher risk than Mounjaro) Semaglutide (Wegovy/Ozempic): ROR 2.04 (suggests the reporting rate is about 2 times higher than expected, slightly lower than Mounjaro) Dulaglutide (Trulicity): ROR 2.01 (suggests the reporting rate is about 2 times higher than expected, slightly lower than Mounjaro) While these numbers may seem complicated, they suggest that Mounjaros pancreatitis risk is comparable to or lower than that of other medications in the same class, with liraglutide showing a notably higher risk signal
A While some people feel changes after just one session, noticeable improvements usually require repeated treatments
