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and c) irregular dietary patterns), reduced bioavailability (impairment of the intrinsic factor-mediated absorption pathway, often due to the widespread and prolonged use of proton pump inhibitors), and malabsorption syndromes
After the initial 4 months, a subset of participants (270) continued the treatment for an additional 42 months in a single-blind extension phase, focused on weight maintenance
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NMN and NR , the precursors B3 derivatives well reported to increase NAD+ levels
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