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The number of adults prescribed a GLP-1 without a type 2 diabetes diagnosis jumped nearly 1,961% during the same period (Figure 1)
Therefore, current evidence should be interpreted as supporting primarily weight-loss-associated symptomatic and functional benefit, rather than established direct joint-level disease modification (McGowan et al., 2025
They are generally well-tolerated and easily absorbed, making them a popular choice for supporting gut and immune health
GLP-1s are high-cost medications, and while short-term results are strong, adherence over time tends to drop
Engage in regular physical activity: Aim for at least 150 minutes of moderate-intensity aerobic activity per week (brisk walking or cycling), plus strength training exercises at least twice a week
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