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For the standalone 5-Amino-1MQ overview, see What Is 5-Amino-1MQ
Those who follow a vegetarian or vegan diet may have trouble getting enough B12 from food alone
A 2025 European Journal of Clinical Nutrition commentary on the NICE guideline argued that the diagnostic threshold and clinical awareness still need to be tightened further, especially around pernicious anaemia, which is still under-recognised in primary care
Patients considering B12 injections should consult their GP for proper assessment and, if indicated, receive treatment through NHS services where safety standards and clinical governance are maintained
While supplementing with up to 2,000 mcg of B12 is considered safe for treating deficiencies, it is advisable to consult a healthcare professional to determine if supplementation is necessary, especially if you are taking medications or are pregnant
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