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B-100 complex can interfere with other medications including but not limited to levodopa, medicines containing oestrogen, hydrazine, certain anti epileptic drugs, phenobaritone, phenytoin, immunosuppressants and some medicines used to treat infections such as isoniazid, pyrazinamide, cycloserne and penicillamine

For others, like chronic celiac or Crohns disease, you may need B12 injections throughout your life

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