Traditionally prescribed under the brand names Ozempic and Rybelsus, Semaglutide by Novo Nordisk takes a multifaceted approach to diabetes care, weight loss, and heart health
Khrom, a board-certified dermatologist and fellowship-trained Mohs surgeon, brings over 15 years of experience in cosmetic and medical dermatology, including laser treatments, facial reconstruction, and advanced aesthetic injectables
The most important serious side effects include acute pancreatitis (severe persistent abdominal pain radiating to the back, though clinical trials found similar pancreatitis rates to comparators), severe dehydration from persistent vomiting or diarrhea (signs include dizziness, decreased urination, extreme thirst), gallbladder disease including cholecystitis or cholelithiasis (right upper quadrant pain, fever, jaundice), severe allergic reactions (difficulty breathing, swelling of face or throat), and severe hypoglycemia when combined with insulin or sulfonylureas (confusion, loss of consciousness, seizures)
And throughout, only use sterile technique, carefully calculate doses, and be willing to stop altogether at the first sign of unusual side effectsespecially changes in nevi or new pigmented lesions
doi: 10.1016/j.ejmech.2016.12.020 37 GallwitzB