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Roesel RA, Hommes FA, Samper L: Pyroglutamic aciduria (5-oxoprolinuria) without glutathione synthetase deficiency and with decreased pyroglutamate hydrolase activity

When you swallow a traditional pill, the harsh acids in your stomach and the enzymes in your digestive tract tend to break the molecule down into its individual amino acids before it can reach the small intestine for absorption

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While semaglutide is powerful, continuous use over many years without reevaluation might not be suitable for everyone