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Cardiovascular disease The number of deaths attributed to heart failure is increasing worldwide and has become a global health issue
A useful comparison point is the acylation chemistry described for semaglutide by Lau and colleagues in the Journal of Medicinal Chemistry in 2015 [2], which introduced a C18 diacid linked through a spacer to achieve albumin binding on a GLP-1 scaffold
Medications that are most effective may have a higher risk of adverse effects
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