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Abstract A central process contributing to the phenotype of aging is cellular senescence

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showed that SCO alone reduced the expression of apoptosis-associated speck-like protein containing a CARD (ASC), IL-1, TNF- and IL-6, inhibited the activation of NLRP3 inflammasome in the liver, and increased the levels of the antioxidants CAT and SOD, thus ameliorating liver inflammation (33)