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We also evaluated acute treatment with tirzepatide, a dual GLP-1/gastric inhibitory peptide (GIP) receptor agonist, and retatrutide, a triple GIP/GLP-1/glucagon receptor agonist, to determine whether broader receptor activity would differentially influence alcohols subjective effects
Though rare, side effects can happen
There have also been anecdotal reports of insomnia as a side effect, although the drugs manufacturer, Novo Nordisk, does not list it as a known adverse effect
Clinical trials demonstrate that semaglutide reduces body weight by up to 22% in adults with obesity or overweight status
Current evidence does not show that GLP-1 receptor agonists directly trigger intestinal inflammation or Crohn's flares
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