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Unlike PDE5 medicines that work mainly on blood vessels, this bremelanotide therapy influences the brains arousal circuits
Research confirms that Pycnogenol enhances endothelial NO production by increasing endothelial nitric oxide synthase (eNOS) activity and protects the generated NO from degradation by scavenging superoxide anion radicals, thereby improving its bioavailability (250)
These therapies remain highly effective, but like any fast-growing category, theyre being evaluated closely as use scales
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