Addressing its poor solubility, rapid metabolism, and low membrane permeability through delivery systems including nanocarriers may prove beneficial, but research is limited
Saxenda: nausea, diarrhea, constipation, vomiting, injection site reactions, headache, low blood sugar, upset stomach, fatigue, dizziness, abdominal pain, increased lipase (a digestive enzyme), upper abdominal pain, fever, and gastroenteritis (inflammation of the stomach and intestines)
Fisher FM, McTernan PG, Valsamakis G, Chetty R, Harte AL, Anwar AJ, et al
3 Treatment of Severe Hypoglycemia Neuroglycopenia can impair an individual to the extent that someone else must administer treatment
A Y1R germline deletion results in elevated osteoblast activity and mineral apposition rate, together with increased formation of highly multinucleated osteoclasts and enhanced surface area, demonstrating a negative role of Y1R on bone mass maintenance [76]