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Other teaching points Physicians should recognize that, at times, several concurrent conditions with overlapping symptoms and signs may collectively contribute to the overall clinical picture of the patient, rather than attributing it solely to a single explanatory cause

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the methyl group at the 1-position and the amino group at the 5-position appear important for inhibitory activity

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Trial and label protocols hold the current step when nausea, vomiting, constipation, reflux, or food aversion has not settled