Thyroid evidence boundary Jastreboff 2023 ( NEJM , NCT04881760), Rosenstock 2023 ( Lancet , NCT04867785), Sanyal 2024 ( Nature Medicine , NCT04881760), and the posted TRIUMPH-1 and TRIUMPH-4 toplines did not publish targeted Free T3, Free T4, or TSH outcomes
Injections can be weekly while refills are made on follow-ups.
If a compound has a 4-hour half-life, its concentration will be halved every 4 hours
They then increased the EAR by 20% to arrive at an RDA of 2.4 g which aims to cover the needs of 97% to 98% of the population
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