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Thermoregulation: The antipyretic effect is mediated via the hypothalamus, the bodys thermoregulatory center

These effects have been observed in both acute wounds and chronic, non-healing wounds

Additional renal effects of hyperuricemia include metabolic acidosis caused by defective lactic acid excretion which in turn exacerbates the hyperuricemia due to reduced urate excretion

The low P app values (Fig

In terms of anti-thrombotic effects, FeM@Sr-TNK nanoparticles utilize magnetic targeting technology to precisely deliver nanoparticles to thrombotic sites, combining their loaded TNK-tPA to achieve rapid thrombolysis, thereby opening blocked vessels and significantly improving microcirculatory dysfunction after reperfusion