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Snake venom metalloproteinases (SVMPs): a structurefunction update

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In detail, ROS are involved in disturbing antioxidant defenses, the mitochondria, microtubule, ion channels, and biomolecular functions, as well as inducing neuroinflammation, demyelination, and neuronal apoptosis in the process of PIPN (Areti et al., 2014)

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