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Semaglutide is absolutely contraindicated in patients with a personal or family history of medullary thyroid carcinoma (MTC) or in patients with multiple endocrine neoplasia syndrome type 2 (MEN 2)
Furthermore, ferroptosis execution-related proteins such as arachidonate 15-lipoxygenase ( ALOX15 ) and HMOX1 were significantly upregulated in the serum of DKD patients and closely related to inflammatory markers (Zhao et al., 2025b)
Athanasios Jamurtas, University of Thessaly, Greece
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