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The individual recovered but later withdrew from the trial
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Aside from direct membrane attack, other mechanisms for amyloid antimicrobial activities include the induction of protein aggregation within the bacteria itself leading to death, conformational changes to microbial proteins by amyloid binding, thereby inhibiting their function or agglutination of microbes into large aggregates (Chen et al., 2022)
There is growing interest in how metabolic interventions, like ketogenic diets or intermittent fasting, might enhance brain energy metabolism by modulating astrocytic functions (Bak et al., 2018)
