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Several studies confirm that long-term treatment with non-steroidal anti-inflammatory drugs (NSAIDs) that non-selectively inhibit cyclooxygenases COX-1 and COX-2, such as ibuprofen, reduce the risk of AD by the inhibition of the inflammatory cascade [13,14,15]

Subsequently, the samples underwent dehydration using an ethanol gradient and were embedded in Eponate 12 resin