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Limitations of article search and selection From the systematic review itself, although over one million initial results were produced, more search terms could have been included, specifically brand names of the GLP-1 RA medications and specific names of surgeries or procedures

Onset of xenobiotic metabolism in children: toxicological implications

However , some local side effects are possible

Some, like Leptin, introduced in 1999, managed to produce limited weight loss without severe side effects but not enough to be worthwhile

If the manufacturer of a medication specifies a particular diluent (e.g., sterile saline), bacteriostatic water should not be substituted unless approved, and if used, the osmolarity of the mixture must be considered